Category Muscle Growth and Hormone Optimization

IGF 1LR3 .1mg

Name: IGF 1LR3 .1mg - Hira Compounds
Price: 35.00 USD
Availability: InStock

Price $35.00

Vials Single ×1

You Save $0.00

Only $35.00/vial — Final price per vial after savings

In Stock

IGF-1 LR3 .1mg (Insulin-like Growth Factor-1 Long Arg3) is a synthetic analog of naturally occurring IGF-1. It is engineered with specific amino acid modifications that drastically reduce its binding to carrier proteins. This allows the peptide to remain biologically active in the bloodstream for a significantly extended duration.

Designed for professional laboratory environments, IGF-1 LR3 .1mg is intended strictly for analytical and experimental research purposes only.

Product Specifications

Compound Name: IGF-1 LR3
Strength: 1mg
Form: Lyophilized Powder
Purity: ≥99% Research Grade
Appearance: White / Off-White Powder
Packaging: Sterile Multidose Vial
Storage: Store in a cool, dry environment away from heat and direct light

Bulk Discounts

Quantity	Discounted Price
5 – 9 items	37% OFF
10+ items	57% OFF

Select pack size

For laboratory research use only. Not for human or animal consumption.

Batch No. Report No. Tested Purity COA

Complete your protocol

Lyophilized peptides need bacteriostatic water and a syringe to reconstitute. Add the essentials in one click.

IGF 1LR3 .1mg In your order

Reconstitution Solution - 3ML $7.00 Required

Core Mechanism of Action

Naturally occurring IGF-1 is heavily regulated by Insulin-like Growth Factor Binding Proteins (IGFBPs), which sequester the peptide and limit its availability. IGF-1 LR3 bypasses this restriction through two key modifications:

1. Arginine Substitution: An arginine replaces glutamic acid at the third position of the amino acid sequence.
2. N-Terminal Extension: A 13-amino-acid extension is added to the N-terminus.

Because of these structural changes, IGF-1 LR3 cannot bind to the body’s natural IGFBPs. This alteration provides two major biochemical advantages:

Extended Half-Life: While native IGF-1 has a half-life of only 12 to 15 minutes, IGF-1 LR3’s half-life is extended to roughly 20 to 30 hours.
Increased Potency: By remaining "free" in circulation, the peptide retains an extremely high affinity for the IGF-1 Receptor (IGF-1R). It is considered approximately three times more potent than native IGF-1.

Biological Effects

Once IGF-1 LR3 binds to IGF-1 receptors on target tissues—primarily in skeletal muscle, bone, and connective tissues—it initiates several downstream biological cascades:

Hypertrophy and Hyperplasia: The peptide activates the Akt/mTOR pathway, which promotes both cellular enlargement (hypertrophy) and the multiplication or creation of entirely new muscle fibers (hyperplasia).
Protein Synthesis: It upregulates the translation of messenger RNA (mRNA) into proteins, allowing for more efficient tissue repair and cellular growth.
Nutrient Partitioning: It increases cellular glucose uptake and amino acid transport, while concurrently influencing lipid metabolism and promoting the utilization of fatty acids for energy.

Key Features

Premium research-grade peptide
High-purity laboratory-tested formulation
Reliable and consistent quality
Sterile sealed vial packaging
Suitable for scientific and peptide research applications

Research Applications

IGF-1 LR3 is commonly researched in peptide and biochemical laboratory studies. This compound is supplied exclusively for scientific analysis, laboratory investigation, and research development purposes.

Important Disclaimer

FOR RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
This product is not intended to diagnose, treat, cure, or prevent any disease. Handling should only be performed by qualified professionals and licensed researchers in appropriate laboratory settings.