SLU-PP-332 (Pan-ERR Agonist) is a synthetic small-molecule compound engineered to target Estrogen-Related Receptors. Classified in preclinical literature as an exercise mimetic, SLU-PP-332 activates transcription programs that regulate cellular energy expenditure, oxidative capacity, and mitochondrial biogenesis.
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SLU-PP-332 Capsules
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Primary Research Mechanisms
Pan-ERR Activation: SLU-PP-332 functions as a potent pan-agonist, exhibiting high affinity.
Mitochondrial Biogenesis & Function: By interacting with the PGC-alpha ERR axis, SLU-PP-332 upregulates gene networks responsible for mitochondrial expansion, oxidative phosphorylation, and cellular respiration.
Fatty Acid Oxidation: Pharmacological stimulation shifts cellular metabolism toward prioritizing lipid substrates over glucose, driving efficient fatty acid breakdown.
Exercise-Mimetic Gene Signature: In animal models, administration of SLU-PP-332 induces a transcriptional response in skeletal muscle that closely mirrors endurance exercise, increasing oxidative fiber characteristics (Type IIa) without requiring active physical conditioning.
Chemical Specifications
CAS Number: 2922119-02-0
Molecular Formula: C18/H14/N2/O2
Molecular Weight: 290.32 g/mol
Class: Synthetic Small Molecule / Nuclear Receptor Agonist.
RESEARCH USE ONLY: This compound is strictly intended for laboratory experimentation and in vitro or in vivo scientific research. It is not approved for human consumption, clinical trials, or therapeutic/veterinary use. Always handle in compliance with relevant safety and regulatory guidelines.
| Purity | ≥ 99% (HPLC) |
|---|---|
| Appearance | White lyophilized powder |
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